Not much is notable about the lecherous Ataru Moroboshi, but his extraordinary bad luck sticks out like the horns in an alien's head. When Earth is threatened by a fleet of alien invaders known as the Oni, Ataru is selected to represent humanity in a duel against one of them. It's a stroke of rare luck for Ataru that the duel is in fact a game of tag, and that his opponent is Lum, daughter of the Oni's leader, who places her personal dignity above victory—as Ataru finds out by seizing Lum's bikini top and with it, victory. However, misfortune kicks in again when Lum mistakes Ataru's promise to marry his girlfriend, Shinobu Miyake, as the desire to wed Lum herself, and decides she rather likes the idea. Wielding her influence as an alien princess, she moves in with him. Forced to deal with the consequences of his womanizing ways, Ataru must balance his crumbling relationship with Shinobu while keeping Lum happy, all the while flirting with every woman he meets.

Winning the high school team tournament was a great accomplishment for the Mizusawa members. Each of them has made great strides in improving themselves, and the victory symbolizes how far they've come. But after accomplishing one goal, their individual aims are within reach. Chihaya Ayase has her sights set on Wakamiya Shinobu and the title of Queen, and now that Taichi Mashima has made it into Class A, he can finally compete against Arata Wataya. Everyone in Mizusawa wants to get better, and there's no telling what the future holds if they keep trying.

Ikebukuro is home to many different businesses and gangs. This includes Makoto Majima: the infamous "troubleshooter" who mediates between warring factions. Makoto knows all of the ins and outs of the bustling Tokyo district and strives to maintain peace alongside the G-Boys, who assist Makoto in his troubleshooting endeavors. Led by the charismatic and ruthless Takashi Andou, the G-Boys is the most influential gang in all of Ikebukuro. However, when the new faction "Red Angels" begins to move in on the G-Boys' turf, immediate tensions rise between them. With numerous enemies scattered around and within the G-Boys, navigating through the streets becomes more difficult for Makoto. While continuing to troubleshoot problems, he slowly unravels a plot that may trigger an all-out war and threaten the entirety of Ikebukuro.

As the elegant, frail flower petals wither away into lifeless ashes, the young duke is tragically reminded of the despicable power forced upon him—the ability to kill anything he touches. Scorned by his family, he is sent away to live in near isolation. Fortunately, he is not entirely alone, as the manor's staff— his dutiful butler Rob and the flirtatious maid Alice—keep him company and make his life less miserable. As the duke's romantic feelings for Alice grow, so does his continued frustration for the limits set by his unfortunate ability. Therefore, he resolves to break the curse cast upon him all those years ago, not only for his sake, but Alice's as well—for he is painfully aware of how difficult it is to avoid the touch of a loved one.