Lee Myeongyi has lived his whole life with pneumothorax—a collapsed lung. He despises the attention he draws at school with his bouts of loud hyperventilating, extended coughing fits, and exemption from physical education as well as military service. Whether suffering through the curiosity or ire of his classmates, Myeongyi is left feeling like a complete outcast. However, the class president Han Seonho often shows Myeongyi kindness and understanding. With his friendly gestures and handsome looks, he becomes Myeongyi's first crush. Nine years later, Myeongyi attends his high school reunion for only one reason: to see Han Seonho once again. He holds a tiny glimmer of hope about the other man's feelings for him—but after seeing the bright gold ring on Seonho's left hand and listening to their classmates' prying questions, that hope is quickly dashed. Excusing himself to go take a smoke, regardless of the state of his lungs, Myeongyi is followed outside by Seonho. Unexpectedly, that marks the beginning of their illicit love affair.

Shun Hashimoto is an openly gay aspiring novelist living in Okinawa who was abandoned by his parents after coming out to them. Mio Chibana is a reserved, orphaned high school student, often found spending his time by the sea. One day, the two meet on the beach, and Shun is instantly captivated by Mio. The days fly by as they slowly begin to grow closer until Mio suddenly announces that he has to leave for the mainland. Three years pass before a 20-year-old Mio returns to Okinawa to confess his love to Shun. However, in those three years, Shun's life has changed. Will he be able to accept Mio's feelings and make such a commitment?

The school love story is set at Baramon High School, a private boys' school for the prefecture's most elite. The protagonist is a seventeen year old boy who transfers into the school and meets various major players on campus, such as the outlaw teacher, the soccer captain, and a childhood friend whom the protagonist has not seen for seven years. The school presents opportunities for friendship, love and conflict, and changes are now bound to happen in the main character's life.

The July issue of Dear+ has announced that a series of manga serialized in the magazine will get anime adaptations in celebration of the magazine's 20th anniversary. These anime will be collected into an "in motion" animation series titled 6 Lovers.