Thirty-seven-year-old Satoru Mikami is a typical corporate worker, who is perfectly content with his monotonous lifestyle in Tokyo, other than failing to nail down a girlfriend even once throughout his life. In the midst of a casual encounter with his colleague, he falls victim to a random assailant on the streets and is stabbed. However, while succumbing to his injuries, a peculiar voice echoes in his mind, and recites a bunch of commands which the dying man cannot make sense of. When Satoru regains consciousness, he discovers that he has reincarnated as a goop of slime in an unfamiliar realm. In doing so, he acquires newfound skills—notably, the power to devour anything and mimic its appearance and abilities. He then stumbles upon the sealed Catastrophe-level monster "Storm Dragon" Veldora who had been sealed away for the past 300 years for devastating a town to ashes. Sympathetic to his predicament, Satoru befriends him, promising to assist in destroying the seal. In return, Veldora bestows upon him the name Rimuru Tempest to grant him divine protection. Now, liberated from the mundanities of his past life, Rimuru embarks on a fresh journey with a distinct goal in mind. As he grows accustomed to his new physique, his gooey antics ripple throughout the world, gradually altering his fate.

Takemichi Hanagaki’s second year of middle school was the highest point in his life. He had respect, a gang of friends he could count on, and even a girlfriend. But that was twelve years ago. Today, he’s a nobody: a washed-up nonentity made fun of by children and always forced to apologize to his younger boss. A sudden news report on the Tokyo Manji Gang’s cruel murder of the only girlfriend he ever had alongside her brother only adds insult to injury. Half a second before a train ends his pitiful life for good, Takemichi flashes back to that same day twelve years ago, when he was still dating Hinata Tachibana. After being forced to relive the very same day that began his downward spiral, Takemichi meets Hinata’s younger brother. Without thinking, he admits to his seeming death before flashing back to the past. Takemichi urges him to protect his sister before inexplicably returning to the future. Miraculously, he isn’t dead. Stranger still, the future has changed. It seems as though Takemichi can alter the flow of time. Given the chance to prevent his ex-girlfriend’s tragic death at the hands of the Tokyo Manji Gang, Takemichi decides to fly through time to change the course of the future.

Aslan Jade Callenreese, known as Ash Lynx, was a runaway picked off the streets of New York City and raised by the infamous godfather of the mafia, Dino Golzine. Now 17 years old and the boss of his own gang, Ash gets his hands on a mysterious drug called "Banana Fish"—the same two words his older brother, Griffin, has muttered since his return from the Iraq War. However, his investigation is hindered when Dino sends his men to retrieve the drug from Ash at an underground bar he uses as a hideout. At the bar, Skip, Ash's friend, introduces him to Shunichi Ibe and his assistant, Eiji Okumura, who are Japanese photographers reporting on American street gangs. However, their conversation is interrupted when Shorter Wong, one of Ash's allies, calls to warn him about Dino. Soon, Dino's men storm the bar, and in the ensuing chaos kidnap Skip and Eiji. Now, Ash must find a way to rescue them and continue his investigation into Banana Fish, but will his history with the mafia prevent him from succeeding?

Seven years after the events of Dragon Ball Z, Earth is at peace, and its people live free from any dangers lurking in the universe. However, this peace is short-lived; a sleeping evil awakens in the dark reaches of the galaxy: Beerus, the ruthless God of Destruction. Disturbed by a prophecy that he will be defeated by a "Super Saiyan God," Beerus and his angelic attendant Whis start searching the universe for this mysterious being. Before long, they reach Earth where they encounter Gokuu Son, one of the planet's mightiest warriors, and his similarly powerful friends.